Kai'Sa is a highly mobile marksman commonly played in the Dragon Lane as an ADC. Unlike other ADCs, Kai'Sa mostly does Magic Damage. Kai’Sa should max (1) Icathian Rain until it's maxed, then focus on (3) Supercharge, and finally (2) Void seeker. Level up your ultimate whenever possible.
When Playing as Kai’Sa, build Manamune as your first item, this gives you scaling damage and solves her mana issues. After Manamune, build Gluttonous Greaves with a Stasis Enchant if you’re ahead or Guardian Angel if you’re behind as your second item. Finish off your core build with a build a Rabadon's Deathcap or Runaan’s Hurricane as your third item. If you want more attack speed and crit, build Blade of the Ruined King, Phantom Dancer, and Nashor’s Tooth optionally.
The best runes for Kai'Sa are Conqueror keystone with Gathering Storm, Spirit Walker, and Manaflow Band. Players can replace Conqueror for Fleet Footwork if you have a more defensive playstyle.
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